During blood transfusion, agglutination may occur as a result of the reaction between
Answer Details
During blood transfusion, agglutination can occur due to the reaction between contrasting antigens and antibodies. Antigens are proteins found on the surface of red blood cells, which help identify them as belonging to the individual's own body. Antibodies are proteins in the plasma of the blood that help to recognize and fight foreign substances such as bacteria, viruses, and other substances.
When a person receives a blood transfusion, their immune system may recognize the antigens on the red blood cells of the donated blood as foreign and produce antibodies against them. If the donated blood contains antigens that are different from the recipient's own blood, the antibodies produced by the recipient's immune system will bind to these foreign antigens, causing agglutination or clumping of the red blood cells. This agglutination can block blood vessels and prevent oxygen from reaching the body's tissues, causing serious health problems.
Therefore, it is essential to match the blood types of the donor and recipient before a blood transfusion to prevent agglutination and other adverse reactions. This involves testing the blood for the presence of specific antigens and antibodies, and selecting compatible blood types to ensure a safe and successful transfusion.